FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-up.K75N}
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General Information
Symbol
P{UAS-up.K75N}
FlyBase ID
FBtp0143957
Feature type
transgenic_transposable_element
Component Allele(s)
upK75N.UAS
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele upK75N.UAS
Transgenic product class
missense_variant
(Madan et al., 2020)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
up
Description

UASt regulatory sequences drive expression of the RE18550 up cDNA clone, mutated to carry a K75N amino acid substitution. This mutation is equivalent to a K124N change in the orthologous human TNNT2 gene, a cardiomyopathy-associated variant.

(Madan et al., 2020)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-up.K75N}
(FlyBase, 1992-)
UAS-TnTK75N
(Madan et al., 2020)
Secondary FlyBase IDs
    References (3)