FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-hMARK4.ΔG316E317D}
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General Information
Symbol
P{UAS-hMARK4.ΔG316E317D}
FlyBase ID
FBtp0145702
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\MARK4ΔG316E317D.UAS
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\MARK4ΔG316E317D.UAS
Transgenic product class
inframe_deletion
(Oba et al., 2020)
missense_variant
(Oba et al., 2020)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\MARK4
Description

UASt regulatory sequences drive expression of a cDNA that encodes Hsap\MARK4, mutated to carry a double mutation (deletion of residue Gly316 and an E317D amino acid replacement) that is associated with an elevated risk of early-onset Alzheimer disease.

(Oba et al., 2020)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-hMARK4.ΔG316E317D}
(FlyBase, 1992-)
UAS-MARK4ΔG316E317D
(Oba et al., 2020)
Secondary FlyBase IDs
    References (3)