FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-Svip.S82L}
Open Close
General Information
Symbol
P{UAS-Svip.S82L}
FlyBase ID
FBtp0146960
Feature type
transgenic_transposable_element
Component Allele(s)
Size
Expression Data
Associated insertion(s)
Molecular map
Description and Uses
Construct components
Component allele SvipS82L.UAS
Transgenic product class
Component
Use(s)
Encoded product / tool
Description

UAS regulatory sequences drive expression of Svip (sequence from cDNA clone GH02734) that has been mutated to carry a S82L amino acid substitution in the VCP-interaction motif. This change is equivalent to a S77L change in the orthologous human SVIP gene, a variant identified in a patient with sporadic fronto-temporal dementia.

Sequence Data
Sequence (FB)
Associated Sequence Data
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-Svip.S82L}
UAS-SVIPS82L
Secondary FlyBase IDs
    References (3)