FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: M{UAS-hAPOL1.G1.HA}
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General Information
Symbol
M{UAS-hAPOL1.G1.HA}
FlyBase ID
FBtp0151067
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\APOL1G1.UAS.Tag:HA
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\APOL1G1.UAS.Tag:HA
Transgenic product class
missense_variant
(Gerstner et al., 2022)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\APOL1
Tagged with
Tag:HA
Description

UAS regulatory sequences drive expression of the Hsap\APOL1 cDNA (GenBank ID BC112943.1), mutated to carry two amino acid substitutions (p.S342G and p.I384M); this 'G1' version of Hsap\APOL1 is a risk variant for kidney disease. The coding sequence is tagged with Tag:HA.

(Gerstner et al., 2022)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
G1-APOL1
(Gerstner et al., 2022)
G1-APOL1-HA
(Gerstner et al., 2022)
M{UAS-hAPOL1.G1.HA}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (3)