FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: PBac{UAS-hANKLE2.R536C.FLAG}
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General Information
Symbol
PBac{UAS-hANKLE2.R536C.FLAG}
FlyBase ID
FBtp0151899
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\ANKLE2R536C.UAS.Tag:FLAG
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\ANKLE2R536C.UAS.Tag:FLAG
Transgenic product class
missense_variant
(Thomas et al., 2022)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\ANKLE2
Tagged with
Tag:FLAG
Description

UASt regulatory sequences drive expression of a Hsap\ANKLE2 cDNA that has been mutated to carry the R536C amino acid substitution (a microcephaly-associated mutation). The coding sequence is tagged with Tag:FLAG.

(Thomas et al., 2022)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
PBac{UAS-hANKLE2.R536C.FLAG}
(FlyBase, 1992-)
P{UASt-hANKLE2 p.Arg536Cys}
(Thomas et al., 2022)
hANKLE2 p.Arg536Cys
(Thomas et al., 2022)
Secondary FlyBase IDs
    References (3)