FB2026_03 , released September 17, 2026
Recombinant Construct: PBac{drosha.R1210W.GR}
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General Information
Symbol
PBac{drosha.R1210W.GR}
FlyBase ID
FBtp0157374
Feature type
transgenic_transposable_element
Component Allele(s)
droshaR1210W.GR
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele droshaR1210W.GR
Transgenic product class
missense_variant
(Barish et al., 2022)
Component
Use(s)
Regulatory region(s)
drosha
Encoded product / tool
drosha
Description

Genomic fragment that encompasses drosha. The coding sequence has been mutated to carry a R1210W amino acid substitution. This change is equivalent to a R1342W change in the orthologous human DROSHA gene, a variant identified in a patient with a severe neurodevelopmental disorder.

(Barish et al., 2022)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
PBac{drosha.R1210W.GR}
(FlyBase, 1992-)
drosha GR-R1210W
(Barish et al., 2022)
droshaR1210W GR
(Barish et al., 2022)
Secondary FlyBase IDs
    References (3)