FB2026_03 , released September 17, 2026
Recombinant Construct: M{UAS-FLAG.hH3-3A.K27M}
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General Information
Symbol
M{UAS-FLAG.hH3-3A.K27M}
FlyBase ID
FBtp0158311
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\H3-3AK27M.UAS.Tag:FLAG
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\H3-3AK27M.UAS.Tag:FLAG
Transgenic product class
missense_variant
(Jain et al., 2020)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\H3-3A
Tagged with
Tag:FLAG
Description

UASt regulates expression of N-terminally Tag:FLAG-tagged Hsap\H3-3A bearing a K27M mutation that prevents methylation at that residue, and is a recurrent mutation in diffuse midline gliomas and posterior fossa type A ependymomas.

(Jain et al., 2020)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
M{UAS-FLAG.hH3-3A.K27M}
(FlyBase, 1992-)
UASt-H3.3K27M
(Jain et al., 2020)
Secondary FlyBase IDs
    References (4)