FB2026_03 , released September 17, 2026
Recombinant Construct: M{UAS-C-Src42A::dGBP1-HA}
Open Close
General Information
Symbol
M{UAS-C-Src42A::dGBP1-HA}
FlyBase ID
FBtp0158745
Feature type
transgenic_transposable_element
Component Allele(s)
Src42AC.UAS.C-VHH(dGBP1),Tag:HA
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Src42AC.UAS.C-VHH(dGBP1),Tag:HA
Transgenic product class
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Src42A
Tagged with
Tag:HA
VHH(dGBP1)
Description

UASt regulatory sequences drive expression of a fusion protein composed of a truncated, constitutively active form of Src42A (amino acids 214-517, spanning the ATP-binding site and kinase domain, and containing a Y511F mutation in a crucial regulatory residue), the destabilized VHH(dGBP1) nanobody and a Tag:HA tag. The protein is designed to act as an engineered kinase; the VHH(dGBP1) nanobody should target the active kinase domain to proteins that are tagged with GFP (the target of the VHH(dGBP1) nanobody). In the absence of a GFP-tagged target, the nanobody is expected to be degraded.

(Lepeta et al., 2022)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
M{UAS-C-Src42A::dGBP1-HA}
(FlyBase, 1992-)
Src ::dGBP1-HA
(Lepeta et al., 2022)
UAS_Src::dGBP1-HA
(Lepeta et al., 2022)
Secondary FlyBase IDs
    References (3)