FB2026_02 , released June 18, 2026
Recombinant Construct: M{UAS-dGBP1-HA::C-Src42ADead}
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General Information
Symbol
M{UAS-dGBP1-HA::C-Src42ADead}
FlyBase ID
FBtp0158747
Feature type
transgenic_transposable_element
Component Allele(s)
Src42AC.Dead.UAS.N-VHH(dGBP1),Tag:HA
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Src42AC.Dead.UAS.N-VHH(dGBP1),Tag:HA
Transgenic product class
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Src42A
Tagged with
Tag:HA
VHH(dGBP1)
Description

UASt regulatory sequences drive expression of a fusion protein composed of the destabilized VHH(dGBP1) nanobody, a Tag:HA tag and a truncated form of Src42A (amino acids 214-517, spanning the ATP-binding site and kinase domain). The Src42A sequence contains two amino acid substitutions: a Y511F mutation in a crucial regulatory residue, and a K276M mutation that abolishes catalytic activity.

(Lepeta et al., 2022)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
M{UAS-dGBP1-HA::C-Src42ADead}
(FlyBase, 1992-)
UAS_dGBP1-HA::SrcDead
(Lepeta et al., 2022)
Secondary FlyBase IDs
    References (3)