FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{cert.S149L}
Open Close
General Information
Symbol
P{cert.S149L}
FlyBase ID
FBtp0160724
Feature type
transgenic_transposable_element
Component Allele(s)
certS149L
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele certS149L
Transgenic product class
missense_variant
(Gehin et al., 2023)
Component
Use(s)
Regulatory region(s)
cert
Encoded product / tool
cert
Description

cert 5'UTR and coding sequence, expressed under the control of its own promoter. The coding sequence carries a S149L amino acid substitution. This change is equivalent to a S132L change in the orthologous human CERT1 gene, the most common and severe variant identified in patients with ceramide transporter (CerTra) syndrome.

(Gehin et al., 2023)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
P{cert.S149L}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (3)