FB2026_03 , released September 17, 2026
Recombinant Construct: M{UAS-P-mCh-hhC}
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General Information
Symbol
M{UAS-P-mCh-hhC}
FlyBase ID
FBtp0168960
Feature type
transgenic_transposable_element
Component Allele(s)
Size
Expression Data
Associated insertion(s)
Molecular map
Description and Uses
Construct components
Component allele hhC.UAS.PmCherry
Transgenic product class
Component
Use(s)
Encoded product / tool
Description

UAS sequences regulate expression of a fusion protein composed of the hh export signal sequence (codons 1-84), the hh extended N-terminal peptide with a functional palmitoylation acceptor cysteine (codons 85-98), mCherry, amino acids VHG (the three most C-terminal amino acids of the hh signalling domain, the G residue of which is required for cholesteroylation by HhC) and the hh C-terminal domain (HhC, codons 258-472). Autocatalytic cleavage and cholesteroylation by HhC, followed by palmitoylation of the N-terminal acceptor cysteine results in mCherry that is dual-lipidated (with palmitate at the N-terminal end and cholesterol at the C-terminal end).

Sequence Data
Sequence (FB)
Associated Sequence Data
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
M{UAS-P-mCh-hhC}
UAS-PmCherryC
Secondary FlyBase IDs
    References (3)