FB2026_02 , released June 18, 2026
Recombinant Construct: M{UAS-mKcna6.T421I.3xHA}
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General Information
Symbol
M{UAS-mKcna6.T421I.3xHA}
FlyBase ID
FBtp0173972
Feature type
transgenic_transposable_element
Component Allele(s)
Mmus\Kcna6T421I.UAS.Tag:HA
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Mmus\Kcna6T421I.UAS.Tag:HA
Transgenic product class
missense_variant
(Tsai et al., 2025)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Mmus\Kcna6
Tagged with
Tag:HA
Description

UASt sequences regulate expression of Mmus\Kcna6 carrying a T421I amino acid substitution. This change is equivalent to a T421I change in the orthologous human KCNA6 gene, a variant identified in a patient with early-onset epilepsy. The coding sequence is tagged at the C-terminal end with 3xTag:HA.

(Tsai et al., 2025)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
M{UAS-mKcna6.T421I.3xHA}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (3)