FB2026_03 , released September 17, 2026
Recombinant Construct: PBac{UAS-l(2)efl.D113A}
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General Information
Symbol
PBac{UAS-l(2)efl.D113A}
FlyBase ID
FBtp0175166
Feature type
transgenic_transposable_element
Component Allele(s)
l(2)eflD113A.UAS
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele l(2)eflD113A.UAS
Transgenic product class
missense_variant
(Zhao et al., 2026)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
l(2)efl
Description

UASt regulatory sequences drive expression of the coding region of the l(2)efl-RC isoform, mutated to carry a D113A amino acid substitution. This change is equivalent to a D109A mutation in the orthologous human CRYAB gene, a variant associated with disease.

(Zhao et al., 2026)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CryAB D109A
(Zhao et al., 2026)
PBac{UAS-l(2)efl.D113A}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (3)