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| Term | late endosome | ID (Ontology) | GO:0005770 (Gene Ontology) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Definition | A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.[ PubMed:11964142 PubMed:2557062 ] | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Also Known As | "prevacuolar compartment" | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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endomembrane system__ cytoplasmic vesicle__| endosome |__late endosome 167 rec. |__late endosome lumen | |__multivesicular body lumen |__late endosome membrane 27 rec. | |__cytoplasmic side of late endosome membrane | |__endosomal scaffold complex | |__lumenal side of late endosome membrane | |__multivesicular body membrane(+) 1 rec. |__Mon1-Ccz1 complex 4 rec. |__multivesicular body 57 rec. |__multivesicular body lumen |__multivesicular body membrane(+) 1 rec. |__multivesicular body, internal vesicle(+) 5 rec. |
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| Is a | endosome | ||
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Synonyms & Secondary IDs
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External Crossreferences & Linkouts
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| NIF_Subcellular:nlx_subcell_20090702 | |||