FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term late endosome ID (Ontology) GO:0005770 (Gene Ontology)
Definition A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.[ PubMed:11964142 PubMed:2557062 ]
Also Known As"prevacuolar compartment"
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Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Alleles (FBal)PHENOTYPE_MANIFEST_IN
Genes (FBgn)GO_CELLULAR_COMPONENT
Constructs (FBtp)PHENOTYPE_MANIFEST_IN
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 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Constructs
 late endosome (all annotations which use CV term, excluding "NOT" statements)
     colocalizes_with | late endosome       --
      --
     is_active_in | late endosome       --
      --
     late endosome | adult stage
      --
     late endosome | adult stage | increased number
      --
     late endosome | cell autonomous | somatic clone | third instar larval stage
      --
     late endosome | germline clone | oogenesis
      --       --
     late endosome | increased number
      --
     late endosome | larval stage
      --
     late endosome | somatic clone
      --
     late endosome | third instar larval stage
      --
     located_in | late endosome       --
      --
Spanning Tree (Parents/Children)
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Vocabulary search 
endomembrane system__
cytoplasmic vesicle__|
                     endosome
                      |__late endosome  173 rec.
                          |__late endosome lumen
                          |   |__multivesicular body lumen
                          |__late endosome membrane 34 rec.
                          |   |__cytoplasmic side of late endosome membrane
                          |   |__endosomal scaffold complex
                          |   |__lumenal side of late endosome membrane
                          |   |__multivesicular body membrane(+) 1 rec.
                          |__Mon1-Ccz1 complex 4 rec.
                          |__multivesicular body 57 rec.
                              |__multivesicular body lumen
                              |__multivesicular body membrane(+) 1 rec.
                              |__multivesicular body, internal vesicle(+) 5 rec.
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Synonyms
  • "prevacuolar compartment" EXACT
    "PVC" BROAD
Secondary IDs
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NIF_Subcellular:nlx_subcell_20090702