FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term smooth endoplasmic reticulum ID (Ontology) GO:0005790 (Gene Ontology)
Definition The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.[ ISBN:0198506732 ]
Also Known As "SER" ; "smooth ER"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Constructs
 smooth endoplasmic reticulum (all annotations which use CV term, excluding "NOT" statements)       --       2       --
     located_in | smooth endoplasmic reticulum       --       2       --
     smooth endoplasmic reticulum | third instar larval stage       4       --       5
Spanning Tree (Parents/Children)
Only view relationship:
cytoplasm_________________________________
endomembrane system_______________________|
intracellular membrane-bounded organelle__|
                                          endoplasmic reticulum
                                           |__smooth endoplasmic reticulum  7 rec.
                                               |__smooth endoplasmic reticulum cisterna 5 rec.
                                               |   |__hypolemmal cisterna(+)
                                               |   |__subrhabdomeral cisterna 5 rec.
                                               |__smooth endoplasmic reticulum lumen
                                               |__smooth endoplasmic reticulum membrane
                                                   |__cytoplasmic side of smooth endoplasmic reticulum membrane
                                                   |__lumenal side of smooth endoplasmic reticulum membrane
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a endoplasmic reticulum
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "SER" EXACT
    "smooth ER" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
NIF_Subcellular:sao710427438
Wikipedia:Endoplasmic_reticulum#Smooth_endoplasmic_reticulum