FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term smooth endoplasmic reticulum ID (Ontology) GO:0005790 (Gene Ontology)
Definition The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.[ ISBN:0198506732 ]
Also Known As "SER" ; "smooth ER"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
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 Alleles Genes Constructs
 smooth endoplasmic reticulum (all annotations which use CV term, excluding "NOT" statements)       --
      --
     located_in | smooth endoplasmic reticulum       --
      --
     smooth endoplasmic reticulum | third instar larval stage
      --
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cytoplasm_________________________________
endomembrane system_______________________|
intracellular membrane-bounded organelle__|
                                          endoplasmic reticulum
                                           |__smooth endoplasmic reticulum  7 rec.
                                               |__smooth endoplasmic reticulum cisterna 5 rec.
                                               |   |__hypolemmal cisterna(+)
                                               |   |__subrhabdomeral cisterna 5 rec.
                                               |__smooth endoplasmic reticulum lumen
                                               |__smooth endoplasmic reticulum membrane
                                                   |__cytoplasmic side of smooth endoplasmic reticulum membrane
                                                   |__lumenal side of smooth endoplasmic reticulum membrane
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Synonyms
  • "SER" EXACT
    "smooth ER" EXACT
Secondary IDs
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NIF_Subcellular:sao710427438
Wikipedia:Endoplasmic_reticulum#Smooth_endoplasmic_reticulum