FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term cytoskeleton of presynaptic active zone ID (Ontology) GO:0048788 (Gene Ontology)
Definition The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites.[ PubMed:10944438 ]
Also Known As"active zone cytomatrix" ; "pre-synaptic cytoskeletal matrix assembled at active zones" ; "presynaptic cytomatrix assembled at active zones" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Alleles (FBal)PHENOTYPE_MANIFEST_IN
Genes (FBgn)GO_CELLULAR_COMPONENT
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 cytoskeleton of presynaptic active zone (all annotations which use CV term, excluding "NOT" statements)
     colocalizes_with | cytoskeleton of presynaptic active zone       --
     cytoskeleton of presynaptic active zone | third instar larval stage
      --
     located_in | cytoskeleton of presynaptic active zone       --
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cytoskeleton
 |__cortical cytoskeleton__________________________
 |__presynaptic cytoskeleton_______________________|
cell cortex                                        |
 |__cortical cytoskeleton__________________________|
presynaptic active zone                            |
 |__presynaptic active zone cytoplasmic component__|
presynapse                                         |
 |__presynaptic cytoskeleton_______________________|
cell cortex region                                 |
 |__presynaptic active zone cytoplasmic component__|
                                                   cytoskeleton of presynaptic active zone  13 rec.
                                                    |__presynaptic density 1 rec.
                                                        |__T-bar 1 rec.
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Is a cortical cytoskeleton
presynaptic cytoskeleton
Part of presynaptic active zone cytoplasmic component
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Synonyms
  • "active zone cytomatrix" EXACT
    "CAZ" NARROW
    "pre-synaptic cytoskeletal matrix assembled at active zones" EXACT
    "pre-synaptic dense body" NARROW[ PubMed:12575947 ]
    "pre-synaptic ribbon" RELATED[ ISBN:0716723808 ]
    "presynaptic cytomatrix assembled at active zones" EXACT
    "presynaptic cytoskeletal matrix" EXACT syngo_official_label
    "presynaptic cytoskeletal matrix assembled at active zones" EXACT
    "presynaptic dense body" NARROW[ PubMed:16709774 ]
    "presynaptic ribbon" RELATED[ ISBN:0716723808 ]
    "ribbon" RELATED[ PubMed:12575947 ]
    "synaptic ribbon" NARROW[ PubMed:19264728 ]
    "T-bar" NARROW[ PubMed:20127822 ]
    "T-bar ribbon" NARROW[ PubMed:16384719 ]
Secondary IDs
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NIF_Subcellular:sao1470121605