FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term alpha-1,2-mannosyltransferase activity ID (Ontology) GO:0000026 (Gene Ontology)
Definition Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage.[ PubMed:10521541 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 alpha-1,2-mannosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | alpha-1,2-mannosyltransferase activity
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  hexosyltransferase activity
   |__mannosyltransferase activity
       |__alpha-1,2-mannosyltransferase activity  4 rec.
           |__dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity 1 rec.
           |__dol-P-Man:Man(3)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity 1 rec.
           |__dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity 1 rec.
           |__dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity 1 rec.
           |__GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity 1 rec.
           |__lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
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Is a mannosyltransferase activity
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Reactome:R-HSA-446187 "ALG11 transfers the fourth and fifth Man to the N-glycan precursor"
Reactome:R-HSA-446215 "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1"
Reactome:R-HSA-446216 "ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1"
Reactome:R-HSA-4551297 "Defective ALG11 does not transfer Man to the N-glycan precursor"
Reactome:R-HSA-4720478 "Defective ALG9 does not add the seventh mannose to the N-glycan precursor"
Reactome:R-HSA-9035514 "Defective ALG9 does not add the last mannose to the N-glycan precursor"