FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term mannosyltransferase activity ID (Ontology) GO:0000030 (Gene Ontology)
Definition Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 mannosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | mannosyltransferase activity       --
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  glycosyltransferase activity
   |__hexosyltransferase activity
       |__mannosyltransferase activity  28 rec.
           |__alpha-1,2-mannosyltransferase activity 4 rec.
           |   |__dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity 1 rec.
           |   |__dol-P-Man:Man(3)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity 1 rec.
           |   |__dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity 1 rec.
           |   |__dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity 1 rec.
           |   |__GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity 1 rec.
           |   |__lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
           |__alpha-1,3-mannosyltransferase activity 2 rec.
           |   |__dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity 1 rec.
           |   |__GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity 1 rec.
           |__alpha-1,4-mannosyltransferase activity 2 rec.
           |   |__dol-P-Man:GlcN-acyl-PI alpha-1,4-mannosyltransferase activity 1 rec.
           |__alpha-1,6-mannosyltransferase activity 3 rec.
           |   |__dol-P-Man:Man(1)GlcN-acyl-PI alpha-1,6-mannosyltransferase activity 1 rec.
           |   |__dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity 1 rec.
           |   |__GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity 1 rec.
           |   |__initiation-specific glycolipid 1,6-alpha-mannosyltransferase activity
           |__beta-1,4-mannosyltransferase activity 2 rec.
           |   |__chitobiosyldiphosphodolichol beta-mannosyltransferase activity 1 rec.
           |   |__glucomannan 4-beta-mannosyltransferase activity
           |   |__mannan synthase activity
           |__beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity
           |__dolichyl-phosphate beta-D-mannosyltransferase activity 2 rec.
           |__dolichyl-phosphate-mannose-protein mannosyltransferase activity 8 rec.
           |__GlcNAc(2)-PP-Dol mannosyltransferase activity 7 rec.
           |   |__chitobiosyldiphosphodolichol beta-mannosyltransferase activity 1 rec.
           |   |__dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity 1 rec.
           |   |__dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity 1 rec.
           |   |__dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity 1 rec.
           |   |__dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity 1 rec.
           |   |__GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity 1 rec.
           |   |__GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity 1 rec.
           |   |__GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity 1 rec.
           |__GPI mannosyltransferase activity 5 rec.
           |   |__dol-P-Man:GlcN-acyl-PI alpha-1,4-mannosyltransferase activity 1 rec.
           |   |__dol-P-Man:Man(1)GlcN-acyl-PI alpha-1,6-mannosyltransferase activity 1 rec.
           |   |__dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity 1 rec.
           |   |__dol-P-Man:Man(3)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity 1 rec.
           |__heteroglycan alpha-mannosyltransferase activity
           |__inositol phosphorylceramide mannosyltransferase activity
           |__tRNA-queuosine(34) beta-mannosyltransferase activity 1 rec.
           |__undecaprenyl-phosphate mannosyltransferase activity
               |__all-trans-undecaprenyl-phosphate mannosyltransferase activity
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Reactome:R-HSA-162797 "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI"
Reactome:R-HSA-162830 "glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate"
Reactome:R-HSA-446198 "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1"
Reactome:R-HSA-4720497 "Defective ALG12 does not add mannose to the N-glycan precursor"