FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term alpha-1,3-mannosyltransferase activity ID (Ontology) GO:0000033 (Gene Ontology)
Definition Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.[ PubMed:10521541 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 alpha-1,3-mannosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | alpha-1,3-mannosyltransferase activity
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  hexosyltransferase activity
   |__mannosyltransferase activity
       |__alpha-1,3-mannosyltransferase activity  2 rec.
           |__dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity 1 rec.
           |__GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity 1 rec.
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Is a mannosyltransferase activity
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Reactome:R-HSA-446188 "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1"
Reactome:R-HSA-446208 "Addition of a second mannose to the N-glycan precursor by ALG2"
Reactome:R-HSA-4549368 "Defective ALG2 does not transfer a second Man to N-glycan precursor"
Reactome:R-HSA-4720473 "Defective ALG3 does not add mannose to the N-glycan precursor"