FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

G1/S transition of mitotic cell cycle

ID (Ontology)

GO:0000082 (Gene Ontology)

Definition

The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
G1/S transition of mitotic cell cycle (all annotations which use CV term, excluding "NOT" statements)
involved_in \| G1/S transition of mitotic cell cycle

Spanning Tree (Parents/Children)

cell cycle phase transition
 |__mitotic cell cycle phase transition__
 |__cell cycle G1/S phase transition_____|
mitotic cell cycle process               |
 |__mitotic cell cycle phase transition__|
                                         G1/S transition of mitotic cell cycle  37 rec.
                                          |__regulation of G1/S transition of mitotic cell cycle 27 rec.
                                              |__negative regulation of G1/S transition of mitotic cell cycle(+) 15 rec.
                                              |__positive regulation of G1/S transition of mitotic cell cycle(+) 11 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	mitotic cell cycle phase transition cell cycle G1/S phase transition
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-69206 "G1/S Transition"