|
General Information
|
| Term |
SAGA complex |
ID (Ontology) |
GO:0000124 (Gene Ontology) |
| Definition |
A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695).[ PubMed:10637607 PubMed:17337012 PubMed:19056896 PubMed:20838651 PubMed:33004486 ] |
| Also Known As |
"Spt-Ada-Gcn5-acetyltransferase complex" |
| Comment |
|
|
Links to External Ontologies
|
|
QuickGO data AmiGO data
|
|
Annotations
|
|
Records annotated with this term OR any of its CHILD TERMS
|
|
|
|
Records annotated with this exact term (annotations to child terms are NOT included)
|
| Data Class | Field | Records |
|---|
|
| Genes (FBgn) | GO_CELLULAR_COMPONENT | 26 |
|
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
|
| Full annotation statements | Relevant FlyBase reports |
|---|
| Gene Groups | Genes |
|---|
SAGA complex (all annotations which use CV term, excluding "NOT" statements) | 1 | 26 | part_of | SAGA complex | -- | 26 |
|
Relationships
