FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

exosome (RNase complex)

ID (Ontology)

GO:0000178 (Gene Ontology)

Definition

A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.[ PubMed:17174896 PubMed:20531386 PubMed:26726035 ]

Also Known As

"exosome (ribonucleasease complex)" ; "exosome multienzyme ribonuclease complex"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
exosome (RNase complex) (all annotations which use CV term, excluding "NOT" statements)
part_of \| exosome (RNase complex)	--

Spanning Tree (Parents/Children)

cellular anatomical structure
 |__intracellular anatomical structure__
catalytic complex                       |
 |__exoribonuclease complex_____________|
                                        exosome (RNase complex)  14 rec.
                                         |__cytoplasmic exosome (RNase complex) 9 rec.
                                         |   |__bacterial degradosome
                                         |__nuclear exosome (RNase complex) 11 rec.
                                             |__nucleolar exosome (RNase complex)

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	exoribonuclease complex
Part of	intracellular anatomical structure
Synonyms & Secondary IDs
Synonyms
	"exosome (ribonucleasease complex)" EXACT "exosome multienzyme ribonuclease complex" EXACT
Secondary IDs

External Crossreferences & Linkouts