FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term rRNA (adenine-N6,N6-)-dimethyltransferase activity ID (Ontology) GO:0000179 (Gene Ontology)
Definition Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor.[ ISBN:1555811337 PubMed:10690410 ]
Also Known As "18S rRNA dimethylase activity" ; "dimethyladenosine transferase activity" ; "S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 rRNA (adenine-N6,N6-)-dimethyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       2
     enables | rRNA (adenine-N6,N6-)-dimethyltransferase activity       2
Spanning Tree (Parents/Children)
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methyltransferase activity
 |__N-methyltransferase activity_______________
rRNA methyltransferase activity                |
 |__rRNA (adenine) methyltransferase activity__|
                                               rRNA (adenine-N6,N6-)-dimethyltransferase activity  2 rec.
                                                |__16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
                                                |__18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity 1 rec.
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Is a N-methyltransferase activity
rRNA (adenine) methyltransferase activity
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Synonyms
  • "18S rRNA dimethylase activity" EXACT
    "dimethyladenosine transferase activity" EXACT
    "S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase activity" EXACT
Secondary IDs
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Reactome:R-HSA-6790994 "DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851"
Reactome:R-HSA-6793066 "TFB1M dimethylates adenosine-936 and adenosine-937 of 12S rRNA yielding 6-dimethyladenosine-936 and 6-dimethyladenosine-937"