FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term GO:0000225 ID (Ontology) GO:0000225 (Gene Ontology)
Definition Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.[ EC:3 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 GO:0000225 (all annotations which use CV term, excluding "NOT" statements)       1
     enables | GO:0000225       1
Spanning Tree (Parents/Children)
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GO:0016810
 |__GO:0016811__
GO:0160215      |
 |__GO:0019213__|
                GO:0000225  1 rec.
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Is a hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
deacetylase activity
Part of
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Synonyms
  • "6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity" RELATED[ EC:3 ]
    "acetylglucosaminylphosphatidylinositol deacetylase activity" RELATED[ EC:3 ]
    "GlcNAc-PI de-N-acetylase activity" RELATED[ EC:3 ]
    "GlcNAc-PI deacetylase activity" RELATED[ EC:3 ]
    "N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity" RELATED[ EC:3 ]
    "N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.5.1.89
MetaCyc:3.1.1.69-RXN
Reactome:R-HSA-162857 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate"
RHEA:11660