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| Term | THO complex | ID (Ontology) | GO:0000347 (Gene Ontology) | |||||||||
| Definition | The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits.[ PubMed:11060033 PubMed:11979277 PubMed:16983072 ] | |||||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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nucleus_____________________ protein-containing complex__| nuclear protein-containing complex |__THO complex 7 rec. |__nucleoplasmic THO complex 1 rec. |__THO complex part of transcription export complex 6 rec. |
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| Is a | nuclear protein-containing complex | ||
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