FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) ID (Ontology) GO:0000388 (Gene Ontology)
Definition Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).[ ISBN:0879695897 ]
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) (all annotations which use CV term, excluding "NOT" statements)
     involved_in | spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
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mRNA splicing, via spliceosome
 |__spliceosomal conformational changes to generate catalytic conformation__
ribonucleoprotein complex biogenesis                                        |
 |__protein-RNA complex assembly____________________________________________|
protein-RNA complex assembly                                                |
 |__spliceosomal conformational changes to generate catalytic conformation__|
protein-containing complex assembly                                         |
 |__protein-RNA complex assembly____________________________________________|
protein-RNA complex organization                                            |
 |__protein-RNA complex assembly____________________________________________|
                                                                            spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)  1 rec.
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Is a protein-RNA complex assembly
Part of spliceosomal conformational changes to generate catalytic conformation
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Synonyms
  • "3'-splice site cleavage, exon ligation" BROAD
    "spliceosomal A1 complex biosynthesis" NARROW
    "spliceosomal A1 complex formation" NARROW
    "spliceosomal B2 complex biosynthesis" NARROW
    "spliceosomal B2 complex formation" NARROW
    "U12-type spliceosome conformational change to release U4atac and U11" NARROW
    "U2-type spliceosome conformational change to release U4 and U1" NARROW
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