FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term Prp19 complex ID (Ontology) GO:0000974 (Gene Ontology)
Definition A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.[ PubMed:16540691 PubMed:19239890 ]
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT      12
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 Genes
 Prp19 complex (all annotations which use CV term, excluding "NOT" statements)      12
     part_of | Prp19 complex      12
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  cellular_component
   |__protein-containing complex
       |__Prp19 complex  12 rec.
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Synonyms
  • "MOS4-Associated Complex" NARROW[ PubMed:28947490 ]
    "nineteen complex" NARROW
    "NTC" RELATED
    "Prp19/CDC5 complex" NARROW
Secondary IDs
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