FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

DNA-binding transcription factor activity, RNA polymerase II-specific

ID (Ontology)

GO:0000981 (Gene Ontology)

Definition

A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.

Also Known As

"RNA polymerase II transcription factor activity, sequence-specific DNA binding" ; "RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding" ; "sequence-specific DNA binding RNA polymerase II transcription factor activity"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
DNA-binding transcription factor activity, RNA polymerase II-specific (all annotations which use CV term, excluding "NOT" statements)
contributes_to \| DNA-binding transcription factor activity, RNA polymerase II-specific	--
enables \| DNA-binding transcription factor activity, RNA polymerase II-specific	--

Spanning Tree (Parents/Children)

  transcription regulator activity
   |__DNA-binding transcription factor activity
       |__DNA-binding transcription factor activity, RNA polymerase II-specific  498 rec.
           |__DNA-binding transcription activator activity, RNA polymerase II-specific 108 rec.
           |__DNA-binding transcription repressor activity, RNA polymerase II-specific 60 rec.
           |__nuclear receptor activity 23 rec.
               |__bile acid nuclear receptor activity
               |__nuclear steroid receptor activity(+) 4 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	DNA-binding transcription factor activity
Part of
Synonyms & Secondary IDs
Synonyms
	"copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity" NARROW "metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity" NARROW "metal ion regulated sequence-specific DNA binding RNA polymerase II transcription factor activity" NARROW "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity" NARROW "RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity" NARROW "RNA polymerase II transcription factor activity, copper ion regulated core promoter proximal region sequence-specific binding" NARROW "RNA polymerase II transcription factor activity, copper ion regulated proximal promoter sequence-specific DNA binding" NARROW "RNA polymerase II transcription factor activity, metal ion regulated core promoter proximal region sequence-specific binding" NARROW "RNA polymerase II transcription factor activity, metal ion regulated proximal promoter sequence-specific DNA binding" NARROW "RNA polymerase II transcription factor activity, metal ion regulated sequence-specific DNA binding" NARROW "RNA polymerase II transcription factor activity, sequence-specific DNA binding" EXACT "RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding" EXACT "RNA polymerase II transcription factor activity, zinc ion regulated core promoter proximal region sequence-specific DNA binding" NARROW "RNA polymerase II transcription factor activity, zinc ion regulated proximal promoter sequence-specific DNA binding" NARROW "sequence-specific distal enhancer binding RNA polymerase II transcription factor activity" NARROW "sequence-specific DNA binding RNA polymerase II transcription factor activity" EXACT "sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity" RELATED "transcription factor" BROAD "transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" NARROW "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding" NARROW "transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding" NARROW "zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity" NARROW
Secondary IDs

External Crossreferences & Linkouts