FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term cis-regulatory region sequence-specific DNA binding ID (Ontology) GO:0000987 (Gene Ontology)
Definition Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site, located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by some RNA polymerase. Cis-regulatory sites are often referred to as a sequence motifs, enhancers, or silencers.
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      20
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 cis-regulatory region sequence-specific DNA binding (all annotations which use CV term, excluding "NOT" statements)      20
     enables | cis-regulatory region sequence-specific DNA binding      20
Spanning Tree (Parents/Children)
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transcription regulatory region nucleic acid binding__
sequence-specific double-stranded DNA binding_________|
                                                      transcription cis-regulatory region binding
                                                       |__cis-regulatory region sequence-specific DNA binding  395 rec.
                                                           |__RNA polymerase II cis-regulatory region sequence-specific DNA binding 386 rec.
                                                           |   |__cAMP response element binding 2 rec.
                                                           |   |__carbohydrate response element binding
                                                           |   |__E-box binding 11 rec.
                                                           |   |__estrogen response element binding 5 rec.
                                                           |   |__GC-box binding
                                                           |   |__juvenile hormone response element binding 2 rec.
                                                           |   |__N-box binding
                                                           |   |__retinoic acid-responsive element binding
                                                           |   |__RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending
                                                           |   |__serum response element binding
                                                           |   |__sterol response element binding
                                                           |   |__vitamin D response element binding
                                                           |__RNA polymerase III cis-regulatory region sequence-specific DNA binding 8 rec.
                                                               |__RNA polymerase III hybrid type promoter sequence-specific DNA binding
                                                               |__RNA polymerase III type 1 promoter sequence-specific DNA binding 1 rec.
                                                               |__RNA polymerase III type 2 promoter sequence-specific DNA binding 1 rec.
                                                               |__RNA polymerase III type 3 promoter sequence-specific DNA binding 6 rec.
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Is a transcription cis-regulatory region binding
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Synonyms
  • "bacterial-type cis-regulatory region sequence-specific DNA binding" NARROW
    "bacterial-type proximal promoter sequence-specific DNA binding" NARROW
    "bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding" NARROW
    "bacterial-type RNA polymerase enhancer sequence-specific DNA binding" NARROW
    "bacterial-type RNA polymerase upstream activating sequence (UAS) sequence-specific DNA binding" NARROW
    "cis-regulatory region binding" RELATED
    "core promoter proximal region DNA binding" NARROW
    "core promoter proximal region sequence-specific DNA binding" NARROW
    "enhancer binding" RELATED
    "enhancer sequence-specific DNA binding" RELATED
    "eubacterial-type RNA polymerase regulatory transcription factor sequence-specific DNA binding" NARROW
    "promoter proximal region sequence-specific DNA binding" NARROW
    "proximal promoter sequence-specific DNA binding" NARROW
Secondary IDs
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