FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term RNA polymerase I preinitiation complex assembly ID (Ontology) GO:0001188 (Gene Ontology)
Definition The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which includes including UBF, SL1, RRN3 and TBP in human). The PIC engages RNA polymerase I on its DNA template strand and sparks polymerization of the first few RNA nucleotides.[ PubMed:14969726 ]
Also Known As"RNA polymerase I transcriptional preinitiation complex assembly"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 RNA polymerase I preinitiation complex assembly (all annotations which use CV term, excluding "NOT" statements)
     involved_in | RNA polymerase I preinitiation complex assembly
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DNA-templated transcription initiation
 |__transcription initiation at RNA polymerase I promoter__
 |__transcription preinitiation complex assembly___________|
transcription by RNA polymerase I                          |
 |__transcription initiation at RNA polymerase I promoter__|
protein-DNA complex assembly                               |
 |__transcription preinitiation complex assembly___________|
                                                           RNA polymerase I preinitiation complex assembly  2 rec.
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Is a transcription preinitiation complex assembly
Part of transcription initiation at RNA polymerase I promoter
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Synonyms
  • "RNA polymerase I transcriptional preinitiation complex assembly" EXACT
    "RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript" NARROW
    "RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nucleolar primary rRNA transcript" NARROW
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