FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

DNA-binding transcription repressor activity, RNA polymerase II-specific

ID (Ontology)

GO:0001227 (Gene Ontology)

Definition

A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II.

Also Known As

"RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" ; "transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
DNA-binding transcription repressor activity, RNA polymerase II-specific (all annotations which use CV term, excluding "NOT" statements)
contributes_to \| DNA-binding transcription repressor activity, RNA polymerase II-specific
enables \| DNA-binding transcription repressor activity, RNA polymerase II-specific

Spanning Tree (Parents/Children)

DNA-binding transcription factor activity
 |__DNA-binding transcription factor activity, RNA polymerase II-specific__
 |__DNA-binding transcription repressor activity___________________________|
                                                                           DNA-binding transcription repressor activity, RNA polymerase II-specific  60 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity
Part of
Synonyms & Secondary IDs
Synonyms
	"distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific" NARROW "metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in negative regulation of transcription" NARROW "metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" NARROW "proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific" NARROW "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" NARROW "RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in negative regulation of transcription" NARROW "RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" EXACT "RNA polymerase II transcriptional repressor activity, metal ion regulated core promoter proximal region sequence-specific binding" NARROW "RNA polymerase II transcriptional repressor activity, metal ion regulated proximal promoter sequence-specific DNA binding" NARROW "sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in negative regulation of transcription" NARROW "transcriptional repressor activity, metal ion regulated sequence-specific DNA binding" NARROW "transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding" NARROW "transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding" NARROW "transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-8936851 "AHRR binds ARNT"