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| Term | Gi/o-coupled serotonin receptor activity | ID (Ontology) | GO:0001586 (Gene Ontology) | |||||||
| Definition | Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.[ PubMed:18571247 ] | |||||||||
| Also Known As | "5-HT1 receptor activity" ; "serotonin receptor activity, coupled via Gi/o" | |||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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G protein-coupled amine receptor activity |__G protein-coupled serotonin receptor activity |__Gi/o-coupled serotonin receptor activity 2 rec. |
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| Is a | G protein-coupled serotonin receptor activity | ||
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