FB2026_03 , released September 17, 2026
CV Term Report
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Term Gq/11-coupled serotonin receptor activity ID (Ontology) GO:0001587 (Gene Ontology)
Definition Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.[ PubMed:18571247 PubMed:18703043 ]
Also Known As"serotonin receptor activity, coupled via Gq/11"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Gq/11-coupled serotonin receptor activity (all annotations which use CV term, excluding "NOT" statements)
     enables | Gq/11-coupled serotonin receptor activity
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  G protein-coupled amine receptor activity
   |__G protein-coupled serotonin receptor activity
       |__Gq/11-coupled serotonin receptor activity  1 rec.
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Is a G protein-coupled serotonin receptor activity
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  • "5-HT2 receptor activity" BROAD
    "serotonin receptor activity, coupled via Gq/11" EXACT
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