FB2026_03 , released September 17, 2026

CV Term Report

Help Close All Open All

General Information

Term

response to hypoxia

ID (Ontology)

GO:0001666 (Gene Ontology)

Definition

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.

Also Known As

"response to hypoxic stress" ; "response to lowered oxygen tension"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
response to hypoxia (all annotations which use CV term, excluding "NOT" statements)
involved_in \| response to hypoxia

Spanning Tree (Parents/Children)

response to stimulus
 |__response to stress___________________
response to oxygen levels                |
 |__response to decreased oxygen levels__|
                                         response to hypoxia  66 rec.
                                          |__cellular response to hypoxia 32 rec.
                                          |   |__hypoxia-inducible factor-1alpha signaling pathway(+)
                                          |   |__intrinsic apoptotic signaling pathway in response to hypoxia(+)
                                          |   |__regulation of cellular response to hypoxia(+) 3 rec.
                                          |__detection of hypoxia
                                          |   |__detection of reduced oxygen by chemoreceptor signaling(+)
                                          |__response to hypobaric hypoxia

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	response to stress response to decreased oxygen levels
Part of
Synonyms & Secondary IDs
Synonyms
	"response to hypoxic stress" EXACT "response to intermittent hypoxia" NARROW "response to lowered oxygen tension" EXACT "response to sustained hypoxia" NARROW
Secondary IDs

External Crossreferences & Linkouts