FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term mRNA m(6)A methyltransferase activity ID (Ontology) GO:0001734 (Gene Ontology)
Definition Catalysis of the reaction: an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + H+ + S-adenosyl-L-homocysteine. This activity is the methylation of adenines in mRNA with the consensus sequence RRACH, where R is a purine, and H is C, A, or U.[ EC:2 ]
Also Known As "mRNA (N6-adenosine)-methyltransferase activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 mRNA m(6)A methyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       1      2
     enables | mRNA m(6)A methyltransferase activity       --       2
Spanning Tree (Parents/Children)
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RNA methyltransferase activity_____________________________
S-adenosylmethionine-dependent methyltransferase activity__|
                                                           mRNA methyltransferase activity
                                                            |__mRNA m(6)A methyltransferase activity  3 rec.
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Is a mRNA methyltransferase activity
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Synonyms
  • "mRNA (N6-adenosine)-methyltransferase activity" EXACT
Secondary IDs
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EC:2.1.1.348
MetaCyc:RXN-19346
Reactome:R-HSA-72095 "Internal Methylation of mRNA"
RHEA:55584