FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term retinal dehydrogenase (NAD+) activity ID (Ontology) GO:0001758 (Gene Ontology)
Definition Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.[ EC:1 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 retinal dehydrogenase (NAD+) activity (all annotations which use CV term, excluding "NOT" statements)
     enables | retinal dehydrogenase (NAD+) activity
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  aldehyde dehydrogenase [NAD(P)+] activity
   |__aldehyde dehydrogenase (NAD+) activity
       |__retinal dehydrogenase (NAD+) activity  1 rec.
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Is a aldehyde dehydrogenase (NAD+) activity
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Synonyms
  • "cytosolic retinal dehydrogenase activity" RELATED[ EC:1 ]
    "retinal dehydrogenase activity" BROAD
    "retinal:NAD+ oxidoreductase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.2.1.36
MetaCyc:RETINAL-DEHYDROGENASE-RXN
Reactome:R-HSA-5362522 "ALDHs oxidise atRAL to atRA"
Reactome:R-HSA-5696101 "ALDH8A1 oxidises 9cRAL to 9cRA"
RHEA:16177
RHEA:42080
RHEA:42084
RHEA:47132
RHEA:67332