FB2026_03 , released September 17, 2026
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Term cap-dependent translational initiation ID (Ontology) GO:0002191 (Gene Ontology)
Definition The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.[ PubMed:17284590 PubMed:19604130 ]
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 NOT | involved_in | cap-dependent translational initiation
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cytoplasmic translation___
translational initiation__|
                          cytoplasmic translational initiation
                           |__cap-dependent translational initiation
                               |__regulation of cap-dependent translational initiation
                                   |__negative regulation of cap-dependent translational initiation
                                   |__positive regulation of cap-dependent translational initiation
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