FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term DNA binding ID (Ontology) GO:0003677 (Gene Ontology)
Definition Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
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Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 DNA binding (all annotations which use CV term, excluding "NOT" statements)
     contributes_to | DNA binding       --
     enables | DNA binding       --
 NOT | enables | DNA binding       --
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  binding
   |__nucleic acid binding
       |__DNA binding  1138 rec.
           |__bent DNA binding 3 rec.
           |__chromatin DNA binding 94 rec.
           |   |__chromatin insulator sequence binding 17 rec.
           |   |__chromatin loop anchoring activity(+) 4 rec.
           |   |__nucleosomal DNA binding 49 rec.
           |__damaged DNA binding 26 rec.
           |   |__alkylated DNA binding(+)
           |   |__DNA-(abasic site) binding 1 rec.
           |   |__oxidized DNA binding(+) 1 rec.
           |   |__single-strand break-containing DNA binding 1 rec.
           |__DNA binding, bending 5 rec.
           |   |__non-sequence-specific DNA binding, bending
           |   |__sequence-specific DNA binding, bending(+)
           |__DNA end binding
           |__DNA secondary structure binding 13 rec.
           |   |__bubble DNA binding
           |   |__D-loop DNA binding(+)
           |   |__DNA hairpin binding
           |   |__double-strand/single-strand DNA junction binding(+)
           |   |__four-way junction DNA binding(+) 6 rec.
           |   |__heteroduplex DNA loop binding
           |   |__minor groove of adenine-thymine-rich DNA binding 4 rec.
           |   |__Y-form DNA binding 3 rec.
           |__DNA template activity
           |   |__template for synthesis of G-rich strand of telomere DNA activity
           |__double-stranded DNA binding 670 rec.
           |   |__ATP-dependent topological DNA co-entrapment activity
           |   |__DNA-DNA tethering activity(+) 4 rec.
           |   |__double-stranded methylated DNA binding
           |   |__double-stranded telomeric DNA binding 1 rec.
           |   |__hemi-methylated DNA-binding
           |   |__left-handed Z-DNA binding
           |   |__mismatched DNA binding(+) 5 rec.
           |   |__sequence-specific double-stranded DNA binding(+) 626 rec.
           |   |__supercoiled DNA binding
           |__flap-structured DNA binding
           |   |__3'-flap-structured DNA binding
           |   |__5'-flap-structured DNA binding
           |__G-quadruplex DNA binding 2 rec.
           |   |__telomeric G-quadruplex DNA binding
           |__histone-dependent DNA binding
           |__recombination hotspot binding
           |__sequence-specific DNA binding 700 rec.
           |   |__DNA loop anchor binding
           |   |__methyl-CpG binding 1 rec.
           |   |__sequence-specific double-stranded DNA binding(+) 626 rec.
           |   |__sequence-specific single stranded DNA binding(+) 6 rec.
           |   |__telomeric repeat DNA binding(+) 11 rec.
           |   |__unmethylated CpG binding
           |__single-stranded DNA binding 58 rec.
           |   |__C-rich single-stranded DNA binding
           |   |__DNA/DNA annealing activity(+) 3 rec.
           |   |__G-rich single-stranded DNA binding
           |   |__sequence-specific single stranded DNA binding(+) 6 rec.
           |__triplex DNA binding
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Is a nucleic acid binding
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Synonyms
  • "microtubule/chromatin interaction" RELATED
    "plasmid binding" NARROW
    "structure specific DNA binding" RELATED
    "structure-specific DNA binding" RELATED
Secondary IDs
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