FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term DNA clamp loader activity ID (Ontology) GO:0003689 (Gene Ontology)
Definition Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex, driven by ATP hydrolysis.[ PubMed:16082778 ]
Also Known As "DNA clamp loading ATPase activity"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       7
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 DNA clamp loader activity (all annotations which use CV term, excluding "NOT" statements)       1      7
     contributes_to | DNA clamp loader activity       --       6
     enables | DNA clamp loader activity       --       1
Spanning Tree (Parents/Children)
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catalytic activity, acting on DNA__
ATP-dependent activity_____________|
                                   ATP-dependent activity, acting on DNA
                                    |__DNA clamp loader activity  8 rec.
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Is a ATP-dependent activity, acting on DNA
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Synonyms
  • "DNA clamp loading ATPase activity" EXACT
    "DNA-protein loading ATPase activity" RELATED
    "PCNA loading activity" NARROW
    "PCNA loading complex activity" NARROW
    "protein-DNA loading ATPase activity" RELATED
Secondary IDs
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Reactome:R-HSA-174439 "Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere"
Reactome:R-HSA-176264 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"