FB2026_03 , released September 17, 2026
CV Term Report
Help Close All Open All
General Information
Term transcription corepressor activity ID (Ontology) GO:0003714 (Gene Ontology)
Definition A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.[ PubMed:10213677 PubMed:16858867 ]
Also Known As"transcription co-repressor activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

    • Results list data from multiple species. Choose a record type above to open its HitList.
Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
Genes (FBgn)GO_MOLECULAR_FUNCTION
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 transcription corepressor activity (all annotations which use CV term, excluding "NOT" statements)
     contributes_to | transcription corepressor activity       --
     enables | transcription corepressor activity       --
Spanning Tree (Parents/Children)
Only view relationship:
Vocabulary search 
  transcription regulator activity
   |__transcription coregulator activity
       |__transcription corepressor activity  61 rec.
           |__sigma factor antagonist activity
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a transcription coregulator activity
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "RNA polymerase II transcription co-repressor activity" RELATED
    "RNA polymerase II transcription corepressor activity" RELATED
    "transcription co-repressor activity" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-400183 "PPARA:RXRA binds Corepressors of PPARA"