FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term L-glutamate gamma-semialdehyde dehydrogenase activity ID (Ontology) GO:0003842 (Gene Ontology)
Definition L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + 2 H+.
Comment
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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Relevant FlyBase reports
 Gene Groups Genes
 L-glutamate gamma-semialdehyde dehydrogenase activity (all annotations which use CV term, excluding "NOT" statements)       1      2
     enables | L-glutamate gamma-semialdehyde dehydrogenase activity       --       2
 NOT | enables | L-glutamate gamma-semialdehyde dehydrogenase activity       --       1
Spanning Tree (Parents/Children)
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  oxidoreductase activity, acting on the aldehyde or oxo group of donors
   |__oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
       |__L-glutamate gamma-semialdehyde dehydrogenase activity  3 rec.
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Is a oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Part of
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Synonyms
  • "1-pyrroline dehydrogenase" BROAD
    "1-pyrroline-5-carboxylate dehydrogenase activity" RELATED
    "1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity" RELATED
    "delta1-pyrroline-5-carboxylate dehydrogenase activity" RELATED[ EC:1 ]
    "L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity" RELATED
    "pyrroline-5-carboxylate dehydrogenase activity" RELATED[ EC:1 ]
    "pyrroline-5-carboxylic acid dehydrogenase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.2.1.88
MetaCyc:RXN-14116
Reactome:R-HSA-6784399 "ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate"
Reactome:R-HSA-70679 "ALDH4A1 oxidises L-GluSS to Glu"
RHEA:30235