FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term 3-hydroxybutyrate dehydrogenase activity ID (Ontology) GO:0003858 (Gene Ontology)
Definition Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + H+ + NADH.[ EC:1 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 3-hydroxybutyrate dehydrogenase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | 3-hydroxybutyrate dehydrogenase activity
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  oxidoreductase activity, acting on CH-OH group of donors
   |__oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
       |__3-hydroxybutyrate dehydrogenase activity  1 rec.
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Is a oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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Synonyms
  • "D-beta-hydroxybutyrate dehydrogenase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.1.1.30
KEGG_REACTION:R01361
MetaCyc:3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN
Reactome:R-HSA-5696457 "BDH2 dehydrogenates 3HBA"
Reactome:R-HSA-73912 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+"
Reactome:R-HSA-73920 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+"
RHEA:20521