Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Term | branched-chain 2-oxo acid dehydrogenase activity | ID (Ontology) | GO:0003863 (Gene Ontology) |
| Definition | Catalysis of the reaction: N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + 3-methyl-2-oxobutanoate + H+ = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + CO2. Also acts on 4-methyl-2-oxopentanoate and (S)-3-methyl-2-oxopentanoate, so that it acts on the 2-oxo acids that derive from the action of transaminases on valine, leucine and isoleucine. | ||
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oxidoreductase activity, acting on the aldehyde or oxo group of donors |__oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |__branched-chain 2-oxo acid dehydrogenase activity 4 rec. |
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| Is a | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | ||
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EC:1.2.4.4 MetaCyc:1.2.4.4-RXN RHEA:13457 RHEA:84639 RHEA:84643 |
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