FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term 6-phosphofructokinase activity ID (Ontology) GO:0003872 (Gene Ontology)
Definition Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.[ EC:2 ]
Also Known As"6-phosphofructokinase reduction"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 6-phosphofructokinase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | 6-phosphofructokinase activity
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phosphotransferase activity, alcohol group as acceptor__
carbohydrate kinase activity____________________________|
                                                        phosphofructokinase activity
                                                         |__6-phosphofructokinase activity  1 rec.
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Is a phosphofructokinase activity
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Synonyms
  • "6-phosphofructokinase reduction" EXACT
    "6-phosphofructose 1-kinase activity" RELATED[ EC:2 ]
    "ATP-dependent phosphofructokinase activity" RELATED[ EC:2 ]
    "ATP:D-fructose-6-phosphate 1-phosphotransferase activity" RELATED[ EC:2 ]
    "D-fructose-6-phosphate 1-phosphotransferase activity" RELATED[ EC:2 ]
    "fructose 6-phosphate kinase activity" RELATED[ EC:2 ]
    "fructose 6-phosphokinase activity" RELATED[ EC:2 ]
    "nucleotide triphosphate-dependent phosphofructokinase activity" RELATED[ EC:2 ]
    "PFK" RELATED[ EC:2 ]
    "phospho-1,6-fructokinase activity" RELATED[ EC:2 ]
    "phosphofructokinase (phosphorylating)" RELATED[ EC:2 ]
    "phosphofructokinase I activity" RELATED[ EC:2 ]
    "phosphohexokinase activity" BROAD[ EC:2 ]
Secondary IDs
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EC:2.7.1.11
MetaCyc:6PFRUCTPHOS-RXN
Reactome:R-HSA-70467 "PFK tetramer phosphorylates Fru(6)P"
RHEA:16109