FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term DNA ligase (ATP) activity ID (Ontology) GO:0003910 (Gene Ontology)
Definition Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).[ EC:6 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 DNA ligase (ATP) activity (all annotations which use CV term, excluding "NOT" statements)
     enables | DNA ligase (ATP) activity       --
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ligase activity, forming phosphoric ester bonds__
catalytic activity, acting on DNA________________|
                                                 DNA ligase activity
                                                  |__DNA ligase (ATP) activity  4 rec.
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Is a DNA ligase activity
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Synonyms
  • "deoxyribonucleate ligase" BROAD[ EC:6 ]
    "deoxyribonucleic acid joinase" BROAD[ EC:6 ]
    "deoxyribonucleic acid ligase" BROAD[ EC:6 ]
    "deoxyribonucleic acid repair enzyme" RELATED[ EC:6 ]
    "deoxyribonucleic acid-joining enzyme" RELATED[ EC:6 ]
    "deoxyribonucleic joinase" BROAD[ EC:6 ]
    "deoxyribonucleic ligase" BROAD[ EC:6 ]
    "deoxyribonucleic repair enzyme" RELATED[ EC:6 ]
    "deoxyribonucleic-joining enzyme" RELATED[ EC:6 ]
    "DNA joinase activity" BROAD[ EC:6 ]
    "DNA repair enzyme activity" RELATED[ EC:6 ]
    "DNA-joining enzyme" RELATED[ EC:6 ]
    "poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming)" RELATED[ EC:6 ]
    "polydeoxyribonucleotide synthase (ATP) activity" RELATED[ EC:6 ]
    "polynucleotide ligase" BROAD[ EC:6 ]
    "polynucleotide ligase (ATP) activity" RELATED[ EC:6 ]
    "sealase activity" RELATED[ EC:6 ]
Secondary IDs
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EC:6.5.1.1
MetaCyc:DNA-LIGASE-ATP-RXN
Reactome:R-HSA-9914903 "LIG3 (Ligase III) ligates nascent mitochondrial DNA strands"