FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term N-acetylgalactosamine-4-sulfatase activity ID (Ontology) GO:0003943 (Gene Ontology)
Definition Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate.[ EC:3 ]
Also Known As "arylsulfatase B" ; "N-acetylgalactosamine-4-sulphatase activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       4
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 N-acetylgalactosamine-4-sulfatase activity (all annotations which use CV term, excluding "NOT" statements)       1      4
     enables | N-acetylgalactosamine-4-sulfatase activity       --       4
Spanning Tree (Parents/Children)
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  hydrolase activity, acting on ester bonds
   |__sulfuric ester hydrolase activity
       |__N-acetylgalactosamine-4-sulfatase activity  5 rec.
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Is a sulfuric ester hydrolase activity
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Synonyms
  • "acetylgalactosamine 4-sulfatase activity" RELATED[ EC:3 ]
    "arylsulfatase B" EXACT
    "chondroitinsulfatase" BROAD[ EC:3 ]
    "N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity" RELATED[ EC:3 ]
    "N-acetylgalactosamine 4-sulfate sulfohydrolase activity" RELATED[ EC:3 ]
    "N-acetylgalactosamine-4-sulphatase activity" EXACT
Secondary IDs
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EC:3.1.6.12
MetaCyc:3.1.6.12-RXN
Reactome:R-HSA-1606789 "ARSB hydrolyses DS"
Reactome:R-HSA-1793207 "ARSB hydrolyses C4S/C6S chains"
Reactome:R-HSA-2282889 "Defective ARSB does not hydrolyse C4S/C6S chains"
Reactome:R-HSA-9036065 "Defective ARSB does not hydrolyse DS"
Wikipedia:Arylsulfatase_B