FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term NAD+ nucleosidase activity ID (Ontology) GO:0003953 (Gene Ontology)
Definition Catalysis of the reaction: NAD+ + H2O = ADP-D-ribose + nicotinamide + H+.[ PubMed:11866528 PubMed:7805847 ]
Also Known As"beta-NAD(+) glycohydrolase activity" ; "diphosphopyridine nucleosidase activity" ; "DPNase activity" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 NAD+ nucleosidase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | NAD+ nucleosidase activity
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  hydrolase activity, acting on glycosyl bonds
   |__hydrolase activity, hydrolyzing N-glycosyl compounds
       |__NAD+ nucleosidase activity  1 rec.
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Is a hydrolase activity, hydrolyzing N-glycosyl compounds
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Synonyms
  • "beta-NAD(+) glycohydrolase activity" EXACT
    "diphosphopyridine nucleosidase activity" EXACT
    "DPNase activity" EXACT
    "NAD glycohydrolase activity" EXACT
    "NAD nucleosidase activity" EXACT
    "NAD(+) glycohydrolase activity" EXACT
    "NADase activity" EXACT
    "nicotinamide adenine dinucleotide glycohydrolase activity" EXACT
    "nicotinamide adenine dinucleotide nucleosidase activity" EXACT
Secondary IDs
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EC:3.2.2.5
MetaCyc:RXN-13859