FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term NADPH dehydrogenase activity ID (Ontology) GO:0003959 (Gene Ontology)
Definition Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 NADPH dehydrogenase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | NADPH dehydrogenase activity       1
Spanning Tree (Parents/Children)
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  oxidoreductase activity
   |__oxidoreductase activity, acting on NAD(P)H
       |__NADPH dehydrogenase activity  2 rec.
           |__NADPH dehydrogenase (quinone) activity 1 rec.
           |__quinone reductase (NADPH) activity
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Is a oxidoreductase activity, acting on NAD(P)H
Part of
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Synonyms
  • "dihydronicotinamide adenine dinucleotide phosphate dehydrogenase activity" RELATED[ EC:1 ]
    "NADPH diaphorase activity" RELATED[ EC:1 ]
    "NADPH-dehydrogenase activity" RELATED[ EC:1 ]
    "NADPH2 diaphorase activity" RELATED[ EC:1 ]
    "NADPH2-dehydrogenase activity" RELATED[ EC:1 ]
    "NADPH:(acceptor) oxidoreductase activity" RELATED[ EC:1 ]
    "NADPH:acceptor oxidoreductase activity" RELATED[ EC:1 ]
    "old yellow enzyme" RELATED[ EC:1 ]
    "OYE" RELATED[ EC:1 ]
    "reduced nicotinamide adenine dinucleotide phosphate dehydrogenase activity" RELATED[ EC:1 ]
    "TPNH dehydrogenase activity" RELATED[ EC:1 ]
    "TPNH-diaphorase activity" RELATED[ EC:1 ]
    "triphosphopyridine diaphorase activity" RELATED[ EC:1 ]
    "triphosphopyridine nucleotide diaphorase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.6.99.1
MetaCyc:NADPH-DEHYDROGENASE-RXN
Reactome:R-HSA-9018867 "5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2"
Reactome:R-HSA-9018901 "5-HEDH dehydrogenates 5(S)-Hp-18(R)-HEPE to 18(R)-RvE2"
RHEA:13149
RHEA:30151