FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term RNA-directed DNA polymerase activity ID (Ontology) GO:0003964 (Gene Ontology)
Definition Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); RNA-template-directed extension of the 3'-end of a DNA strand by one deoxynucleotide at a time.[ EC:2 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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 RNA-directed DNA polymerase activity (all annotations which use CV term, excluding "NOT" statements)       3
Spanning Tree (Parents/Children)
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nucleotidyltransferase activity____
catalytic activity, acting on DNA__|
                                   DNA polymerase activity
                                    |__RNA-directed DNA polymerase activity  3 rec.
                                        |__telomerase activity
                                            |__template for synthesis of G-rich strand of telomere DNA activity
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Is a DNA polymerase activity
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Synonyms
  • "deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity" RELATED[ EC:2 ]
    "DNA nucleotidyltransferase (RNA-directed) activity" RELATED[ EC:2 ]
    "reverse transcriptase activity" RELATED[ EC:2 ]
    "revertase activity" RELATED[ EC:2 ]
    "RNA revertase activity" RELATED[ EC:2 ]
    "RNA-dependent deoxyribonucleate nucleotidyltransferase activity" RELATED[ EC:2 ]
    "RNA-dependent DNA polymerase activity" RELATED[ EC:2 ]
    "RNA-directed DNA polymerase, group II intron encoded" NARROW
    "RNA-directed DNA polymerase, transposon encoded" NARROW
    "RNA-instructed DNA polymerase activity" RELATED[ EC:2 ]
    "RT" RELATED[ EC:2 ]
Secondary IDs
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EC:2.7.7.49
MetaCyc:RNA-DIRECTED-DNA-POLYMERASE-RXN
Reactome:R-HSA-164504 "Synthesis of minus strand strong stop DNA (-sssDNA)"
Reactome:R-HSA-164520 "Minus strand DNA synthesis resumes"