FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term (S)-2-hydroxy-acid oxidase activity ID (Ontology) GO:0003973 (Gene Ontology)
Definition Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + H2O2.
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 (S)-2-hydroxy-acid oxidase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | (S)-2-hydroxy-acid oxidase activity
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  oxidoreductase activity, acting on CH-OH group of donors
   |__oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
       |__(S)-2-hydroxy-acid oxidase activity  1 rec.
           |__(2S)-2-hydroxyphytanate oxidase activity
           |__L-lactate oxidase activity
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Is a oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
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Synonyms
  • "glycolate oxidase activity" RELATED
    "hydroxy-acid oxidase A activity" NARROW[ EC:1 ]
    "hydroxy-acid oxidase B activity" NARROW[ EC:1 ]
    "hydroxyacid oxidase A" RELATED
    "L-2-hydroxy acid oxidase" RELATED
    "L-alpha-hydroxy acid oxidase" RELATED
    "long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity" NARROW
    "medium-chain-(S)-2-hydroxy-acid oxidase activity" NARROW
    "very-long-chain-(S)-2-hydroxy-acid oxidase activity" NARROW
Secondary IDs
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EC:1.1.3.15
MetaCyc:RXN-969
MetaCyc:S-2-HYDROXY-ACID-OXIDASE-RXN
Reactome:R-HSA-389842 "HAO1 tetramer oxidizes glycolate to glyoxylate"
Reactome:R-HSA-6787811 "HAO2 tetramer oxidises 2OH-PALM"
RHEA:16789
RHEA:27662
RHEA:41227